The hospital of the Leper Colony operates in the abandoned Ottoman mosque, which had been constructed on the location where the Catholic church of Saint Barbara used to stand. In the 1930s, the building is expanded, acquiring a reception area to the south and auxiliary spaces to the north (such as a kitchen, storage room, etc.). The tiled roof of the mosque is removed, and a reinforced concrete slab is constructed. The four rooms on either side of the corridor in the original core of the mosque serve as nursing wards.

On the western facade of the hospital, there is an inscription of quicklime, which is visible mainly on rainy days: Here is the Calvary of the 20th century.